The effect of 5-bromodeoxyuridine on early mouse embryos in vitro.
نویسنده
چکیده
The effect of 5-bromodeoxyuridine (BudR) on the development of cleavage stage mouse embryos has been examined. The analogue was found to have a deleterious effect at relatively low doses on survival to blastocyst, and to a lesser extent on trophoblast outgrowth in supplemented medium. No tendency to suppress differentiation rather than cell division was detected. Possible mechanisms for the BudR effect are discussed.
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عنوان ژورنال:
- Journal of embryology and experimental morphology
دوره 32 3 شماره
صفحات -
تاریخ انتشار 1974